The website does not list other citrus fruits, such as blood oranges, as having a negative interaction with Lipitor. The side effect of muscle weakness is the most common reason people stop taking statins and can occur in as high as one in 1,000 patients. Throwing up and I am on meds and have been drinking grapefruit juice? Very Important. Different foods have adverse interactions with different medications. This enzyme is essential for breaking down Lipitor and other statin drugs. Are there affects of drinking grapefruit juice while taking soma? Duur viagra and can you drink orange juice when taking lipitor. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Drugs & Medications Lipitor. Learn More . There is 1 alcohol/food/lifestyle interaction with Lipitor (atorvastatin): Moderate Food Interaction Consumer information for this interaction is not currently available. Orange juice is the juice of an orange. Orange juice also contains high amounts of vitamin C, folate and potassium. A change in your diet, medicine, or dosage may be necessary. Featured on BlackDoctor There are some drugs on the market that come with a warning that states the patient should not take the medication if they also consume orange or other citrus juices (grapefruit, lemon, etc) because of the possibility of potentially dangerous interactions. By OPINION
By MARIE … Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid. This reduces blood flow to the heart and increases the risk of heart disease, stroke and heart attack. The citrus fruit pomelo as well as Seville oranges, known as bitter orange, also may interfere with the metabolism of Lipitor, according to MayoClinic.com. Grapefruit may reduce the intestinal concentration of an certain enzyme by nearly 50 percent, the authors report. Select one or more newsletters to continue. Lipitor decreases the risk of heart attack and stroke in patients with heart disease or at risk of developing the condition. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruit. Atorvastatin, known as the brand Lipitor, is a prescription medication for preventing and treating heart disease. Greater increases in Cmax (up to 71%) and/or AUC (up to 2.5 fold) have been reported with excessive consumption of grapefruit juice (>=750 mL to 1.2 liters per day). At Healthfully, we strive to deliver objective content that is accurate and up-to-date. MayoClinic.com: Grapefruit Juice -- Beware of Dangerous Medication Interactions, American Family Physician: Management of Grapefruit-Drug Interactions, Florida Citrus Mutual: Study -- No Adverse Effects Between Lipitor, Grapefruit Juice. Lipitor decreases the risk of heart attack and stroke in patients with heart disease or at risk of developing the condition. Patients taking the medication may substitute other citrus fruits for grapefruit, Seville oranges and pomelo, notes the website. Can I drink pineapple juice while taking lipitor? She has a Bachelor of Science in psychology. Moore has been published in "Family Circle" magazine and the "Milwaukee Sentinel" newspaper, along with numerous other national and regional magazines, daily and weekly newspapers and corporate publications. Can You Eat a Grapefruit With Hydrochlorothiazide? Will the pineapple juice interfere with the effectiveness of lipitor? Lipitor may negatively interact with grapefruit and certain other citrus fruits, and doctors recommend not eating these particular fruits or drinking their juice when taking Lipitor. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Copyright © 2020 Leaf Group Ltd., all rights reserved. Talk with your doctor about any other substance you consider adding to your health regimen if you take Lipitor. We comply with the HONcode standard for trustworthy health information -. Common Questions and Answers about Lipitor orange juice. In addition, patients should either refrain from the use of oat bran and pectin or, if concurrent use cannot be avoided, to separate the administration times by at least 2 to 4 hours. Considerations. Tangelos, a combination of tangerine and grapefruit, don't contain furanocoumarins, despite a portion of the end-product including genetic material from grapefruit 2. Regular oranges and orange juice are safe to consume with Lipitor. Answer this question. Here’s what you need to know about diet when you’re on a statin for high cholesterol. This can increase the risk of negative effects and lead to toxicity. Like other varieties of oranges, blood oranges are citrus fruits. Orange juice contains a variety of nutrients and phytochemicals, such as vitamin C and citrus flavonoids, that may play a role. Why should you not eat grapefruit while taking atorvastatin. Lipitor also lowers cholesterol and triglyceride blood levels. An OJ a Day Keeps Cholesterol at Bay. The website does not list other citrus fruits, such as blood oranges, as having a negative interaction with Lipitor. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Patients should be advised to promptly report any unexplained muscle pain, tenderness or weakness, particularly if accompanied by fever, malaise and/or dark colored urine. Our team periodically reviews articles in order to ensure content quality. Still looking for answers? Lipitor also lowers cholesterol and triglyceride blood levels. The citrus fruit pomelo as well as Seville oranges, known as bitter orange, also may interfere with the metabolism of Lipitor, according to MayoClinic.com. lipitor. Lipitor orange juice. Lipitor decreases the risk of heart attack and stroke in patients with heart disease or at risk of developing the condition. Myopathy manifested as muscle pain and/or weakness associated with grossly elevated creatine kinase exceeding ten times the upper limit of normal has been reported occasionally. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made. Should I avoid certain foods while taking Lipitor? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Promptly consult your doctor or pharmacist. Dr. Savard says avoiding grapefruit juice is important as it can interfere with how the statin metabolizes in the body. While Lipitor doesn't interact with blood oranges, it does interact with many over-the-counter supplements and medications, and a large number of prescription drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Promptly consult your doctor or pharmacist. Grapefruit, Pomegranate Juice Not a Good Mix With Statins Pomegranate juice, like grapefruit juice, may pose health risks with drugs. She specializes in writing about personal development, health, careers and personal finance. High cholesterol and triglyceride levels can lead to a buildup of these fats on the interior walls of blood vessels, where the accumulation hardens into plaque. Clin Pharmacol Ther 1998 Apr;63(4):397-402. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruit. High cholesterol and triglyceride levels can lead to a buildup of these fats on the interior walls of blood vessels, where the accumulation hardens into plaque. For many years, doctors have recommended avoiding grapefruit while taking statins, but a study sponsored by the Florida Department of Citrus and published in the "British Journal of Clinical Pharmacology" in 2011 found only an insignificant interaction between grapefruit and Lipitor and no negative effects 3. Atorvastatin - Is it safe to stop taking lipitor 10mg abruptly? A change in your diet, medicine, or dosage may be necessary. When a single 40 mg dose of atorvastatin was coadministered with 240 mL of grapefruit juice, atorvastatin peak plasma concentration (Cmax) and systemic exposure (AUC) increased by 16% and 37%, respectively. Should I avoid certain foods while taking Lipitor?
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